Senior Lab Operations Manager Operations Bay Area Bay Area Full-time 150000 - 250000 About Until Until is a moonshot company building a “pause button” for biology. Our near-term focus is organ-scale reversible cryopreservation: preserving donated organs at subzero temperatures without ice formation, then rewarming them uniformly for transplant. By solving this grand challenge, we’re laying the foundation for whole-body reversible cryopreservation, giving patients a bridge to future cures. To achieve our goal, we are assembling an interdisciplinary team to develop perfusion systems, cryoprotectant formulations, and vitrification and rewarming hardware. We envision a future where no transplantable organ is lost to logistics, and no terminal diagnosis is final because patients can safely wait for future medicine to arrive. Role Description We are seeking a Senior Lab Operations Lead to own the day-to-day management and scaling of Until Labs’ research facilities. This role is responsible for ensuring that a large, technically complex laboratory environment operates with high reliability, safety, and throughput. As Until Labs grows, this role will also play a key role in operationalizing expanded lab facilities, including helping stand up and scale into a new space, ensuring continuity of research and readiness for large-animal and GLP-adjacent work. About Until Until is a moonshot company building a “pause button” for biology. Our near-term focus is organ-scale reversible cryopreservation: preserving donated organs at subzero temperatures without ice formation, then rewarming them uniformly for transplant. By solving this grand challenge, we’re laying the foundation for whole-body reversible cryopreservation, giving patients a bridge to future cures. To achieve our goal, we are assembling an interdisciplinary team to develop perfusion systems, cryoprotectant formulations, and vitrification and rewarming hardware. We envision a future where no transplantable organ is lost to logistics, and no terminal diagnosis is final because patients can safely wait for future medicine to arrive. Role Description We are seeking a Senior Lab Operations Lead to own the day-to-day management and scaling of Until Labs’ research facilities. This role is responsible for ensuring that a large, technically complex laboratory environment operates with high reliability, safety, and throughput. As Until Labs grows, this role will also play a key role in operationalizing expanded lab facilities, including helping stand up and scale into a new space, ensuring continuity of research and readiness for large-animal and GLP-adjacent work. Responsibilities

Serve as the operational lead for the move to a new lab facility, in close coordination with leadership, EHS, and external vendors & consultants.

Translate experimental and program needs into facility requirements (space, power, ventilation, gas access, drainage, cold rooms, perfusion areas, BSL space).

Plan and execute lab move logistics: equipment relocation, reinstallation, requalification, and downtime minimization.

Help define lab layout and zoning to support large-organ workflows, animal tissue handling, and clean/dirty separations.

Support day-to-day operations for large-animal model work (e.g., porcine).

Coordinate with external large-animal facilities, CROs, and veterinary teams to ensure smooth experimental execution.

Ensure lab processes are compatible with animal facility constraints, biosafety requirements, and chain-of-custody expectations.

Help adapt internal protocols for work originating from or transitioning into large-animal environments.

Partner with scientists and engineers to operationalize complex, time-sensitive experiments involving large organs and perfusion systems.

Prepare labs, equipment, materials, and personnel for long, high-risk experimental days.

Act as a stabilizing operational presence during critical experimental runs.

Qualifications - Required

5+ years of experience in lab operations, research operations, or senior lab management.

Direct experience supporting large-animal model research (porcine or similar strongly preferred).

Familiarity with large-animal research facilities, workflows, and constraints.

Proven ability to support complex biological experiments.

Experience operating labs during periods of growth, transition, or relocation.

Qualifications - Strongly Preferred

Experience in standing up move into a new lab or research facility.

Exposure to GLP, preclinical, or regulated research environments.

Experience working alongside CROs, veterinary teams, or external animal facilities.

Comfort with cryo-systems, perfusion systems, pressurized systems, or custom hardware-heavy biology.

Benefits

Opportunity for outsized impact creating the future as an early team member

Generous medical, dental, and vision insurance coverage for employees and their dependents

Flexible time off and paid holidays

Competitive compensation package, including salary and equity

Access to a 401(k) retirement savings plan

FSA and commuter benefits

Subsidized lunch daily

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No opportunities available

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